Computer-aided effective fracture risk stratification of patients with vertebral metastases for personalised treatment through robust computational models validated in clinical settings



The BHC, renowned as the preeminent hub for spine medicine within Hungary, stands at the forefront of advancements in this domain. Functioning as a national center of excellence, we undertake globally acclaimed surgical endeavors, guided by a cadre of esteemed experts proficient in the diverse spectrum of spine surgery. Our spine specialists boast extensive experience in addressing an array of spinal conditions, encompassing degenerative alterations, deformities, injuries, neoplastic formations, and inflammatory manifestations. Employing a blend of traditional open surgical procedures and minimally invasive surgical techniques, we strive to optimize healing outcomes through a meticulous integration of scientifically validated practices.

In Hungary, our institution holds a preeminent position as the vanguard of spine surgery. As a national center, we engage in internationally esteemed spine surgical initiatives, benefiting from the collective expertise of specialists spanning the entire spectrum of this specialized field. Within the realm of fundamental and applied research, our medical practitioners leverage their vast experience to contribute to research endeavors of prominent industry leaders at the forefront of spinal surgery innovation. Concurrently, the backbone of our research and development efforts comprises substantial scientific projects executed through extensive international collaborations. Our commitment to enhancing the efficacy of healing processes is underpinned by a foundation of rigorously substantiated scientific research. Notably, the endeavors within our In Silico Biomechanics Laboratory (ISBL) significantly contribute to this pursuit.

Role in Metastra

The hospital's Research and Development Department, specializing in spinal tumors, is at the forefront of innovative medical exploration and advancements. Their dedicated team of researchers and medical experts collaboratively engage in cutting-edge studies, focusing on the etiology, molecular mechanisms, and treatment modalities of spinal tumors. By leveraging state-of-the-art technologies and a multidisciplinary approach, they aim to enhance diagnostic accuracy, develop targeted therapies, and refine surgical techniques for optimal outcomes. This commitment to ongoing research not only furthers scientific knowledge but also translates into improved patient care, offering hope and potential breakthroughs for individuals affected by spinal tumors.

In the context of the METASTRA study, the Buda Health Center (BHC) is actively engaged in the Train-METASTRA initiative, focusing on the retrospective accumulation of clinical and imaging data from a cohort comprising 500 patients afflicted with spinal metastasis. In a subsequent phase, constituting an integral segment of this extensive study, we will initiate the prospective Validate-METASTRA study. The objective of this endeavor is to corroborate and validate the fracture risk stratification model pertaining to spinal metastasis that has been formulated through the assimilation of prospectively collected clinical and radiological data.

Team members

Photo of Aron Lazary
Aron Lazary
Photo of Adam Biczo
Adam Biczo
Photo of Julia Szita
Julia Szita
Kiralyhago utca 1-3
1126 Budapest